Gene Therapy — UPSC Notes
Gene Therapy — UPSC Notes | Legacy IAS GS Paper III · Science & Technology · Biotechnology 💉 Gene Therapy — Fixing the Root Cause of Disease Replacing Defective Genes · Somatic vs Germline · Viral & Non-Viral Vectors · CRISPR-Cas9 · BIRSA 101 (Sickle Cell) · Casgevy (FDA Approved) · Haemophilia Trial at CMC […]
Applications of Biotechnology in Medicine – UPSC Notes
Applications of Biotechnology in Medicine | UPSC Notes | Legacy IAS Bangalore Science & Technology · Biotechnology · UPSC GS-III Applications of Biotechnology in Medicine — Complete Guide 🏥🧬 Complete UPSC Notes — Drug development, diagnostics, gene therapy, CAR-T, stem cells, monoclonal antibodies, tissue engineering, 3D bioprinting, nanomedicine, omics technologies. With real examples, animation, 6 […]
CAR T-Cell Therapy — UPSC Notes
CAR T-Cell Therapy — UPSC Notes | Legacy IAS GS Paper III · Science & Technology · Biotechnology 🛡 CAR T-Cell Therapy — Cancer Immunotherapy Chimeric Antigen Receptor · Personalised Cancer Treatment · T Cell Engineering · NexCAR19 (India’s ₹30 Lakh Therapy) · CD19 & BCMA Targets · CRS Side Effects · 4 Generations · […]
DNA Fingerprinting — UPSC Notes
DNA Fingerprinting — UPSC Notes | Legacy IAS GS Paper III · Science & Technology · Biotechnology 🧬 DNA Fingerprinting — Definition, Process & Applications Sir Alec Jeffreys (1984) · VNTR & STR · PCR Amplification · Gel Electrophoresis · Forensics · Paternity Testing · Wildlife Protection · Lalji Singh (Father of DNA Fingerprinting in […]
DNA Barcoding — Applications & Limitations – UPSC Notes
DNA Barcoding — Applications & Limitations | UPSC Notes | Legacy IAS Bangalore Science & Technology · Biotechnology · UPSC GS-III DNA Barcoding — Every Species Has a Unique ID 🔬 Complete UPSC Notes — What DNA barcoding is (with supermarket barcode analogy), step-by-step process with animation, barcode genes (COI for animals, rbcL/matK for plants, […]
RNA Interference (RNAi) — UPSC Notes
RNA Interference (RNAi) — UPSC Notes | Legacy IAS GS Paper III · Science & Technology · Biotechnology 🔇 RNA Interference (RNAi) — Gene Silencing Nobel Prize 2006 (Fire & Mello) · Post-Transcriptional Gene Silencing · dsRNA → Dicer → siRNA → RISC → mRNA Degradation · 3 Methods: RNA-based · DNA-based · CRISPRi · […]
Recombinant DNA Technology — Process & Applications – UPSC Notes
Recombinant DNA Technology — Process & Applications | UPSC Notes | Legacy IAS Bangalore Science & Technology · Biotechnology · UPSC GS-III Recombinant DNA Technology — The Foundation of Genetic Engineering 🧫 Complete UPSC Notes — What is rDNA, tools (vectors, restriction enzymes, ligase), step-by-step process (made easy with analogies & animation), gene transfer methods, […]
Polymerase Chain Reaction (PCR) — UPSC Notes
Polymerase Chain Reaction (PCR) — UPSC Notes | Legacy IAS GS Paper III · Science & Technology · Biotechnology 🧬 Polymerase Chain Reaction (PCR) Kary Mullis (1983) · Nobel Prize 1993 · DNA Amplification In-Vitro · Taq Polymerase · Thermal Cycling · Denaturation → Annealing → Extension · RT-PCR (COVID-19) · Forensics · Diagnostics · […]
Genome Sequencing Applications, Genome India Project- UPSC Notes
Genome Sequencing — Applications, Genome India Project | UPSC Notes | Legacy IAS Bangalore Science & Technology · Biotechnology · UPSC GS-III Genome Sequencing — Decoding the Blueprint of Life 🧬 Complete UPSC Notes — What is a genome, how sequencing works (made easy!), Human Genome Project, Genome India Project (completed Jan 2025!), IndiGen, Earth […]
Genetic Engineering — Methods, CRISPR, Applications – UPSC Notes
Genetic Engineering — Methods, CRISPR, Applications | UPSC Notes | Legacy IAS Bangalore Science & Technology · Biotechnology · UPSC GS-III Genetic Engineering — Methods, CRISPR, Applications & Ethics 🧬 Complete UPSC Notes — Recombinant DNA technology, CRISPR-Cas9, gene silencing, protoplast fusion. Applications in medicine, agriculture, industry. Ethical concerns: designer babies, gene drives, ecological risks. […]