In the context of recent advances in human reproductive technology, :Pronuclear Transfer: is used for(2020)
a) Fertilization of egg in vitro by the donor sperm
b) Genetic modification of sperm producing cells
c) Development of stem cells into functional embryos
d) Prevention of mitochondrial diseases in offspring
In pronuclear transfer, the mother’s egg is first fertilized with the father’s sperm, producing a zygote. The pronuclei of the egg and sperm are then removed from the zygote and inserted into a donor egg that has been fertilized and has had its own nucleus removed (a pronucleus is the nucleus of the egg or sperm at the stage of fertilization prior to nucleus fusion). The zygote derived from the donor egg is then implanted into the mother’s uterus.