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Shukla takes up experiment on skeletal muscle degradation in space

Mission Update: Group Captain Shubhanshu Shukla at the ISS

  • Group Captain Shukla, known by his mission call sign “Shux”, has begun research activities aboard the ISS following successful adaptation to orbital conditions.
  • As per Axiom Space, the crew has transitioned from arrival protocols to full-scale scientific work.

Relevance : GS 3(Space , Research)

Key Research Areas

Myogenesis Experiment

  • Conducted inside the Life Sciences Glovebox (LSG).
  • Objective: Understand skeletal muscle degradation in microgravity.
  • Potential outcomes:
    • Develop therapies for astronauts to prevent muscle loss during space missions.
    • Advance treatment for muscle-degenerative diseases on Earth.
  • Proposed by: Institute for Stem Cell Science and Regenerative Medicine (InStem), Bengaluru.
  • Part of ISROs microgravity experiment initiative.

Cerebral Hemodynamics Study

  • Focuses on blood flow in the brain under microgravity.
  • Tools: Uses ultrasound technology and real-time monitoring software.
  • Significance:
    • Enhances understanding of cardiovascular changes in space.
    • May improve medical insights into conditions like stroke and hypertension on Earth.

ISRO’s Role and Scientific Goals

  • ISRO has selected seven microgravity experiments for Shukla to conduct during his 14-day stay.
  • Aim: Build a sustainable microgravity research ecosystem in India.
  • Long-term goal: Integrate such experiments into future Indian space missions.

International Scientific Collaboration

  • India-NASA Collaboration:
    • Includes five joint science investigations.
    • Also includes two STEM (science, technology, engineering, and mathematics) outreach experiments.
  • Axiom-4 Mission Scope:
    • Involves ~60 scientific studies.
    • Represents contributions from 31 countries, including:
      • India, U.S., Poland, Hungary, Saudi Arabia, Brazil, Nigeria, UAE, and various European nations.

Significance and Broader Impact

  • Enhances India’s profile in human space research, especially in life sciences and biomedicine.
  • Strengthens India’s collaboration with international space agencies and private players.
  • Provides dual benefit:
    • Supports astronaut health and mission sustainability.
    • Contributes to Earth-based healthcare advancements.

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