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About Enterobacter Bugandensis

Context:

Scientists from the Indian Institute of Technology Madras (IIT-M) and NASA’s Jet Propulsion Laboratory (JPL) have carried out a collaborative study of the behaviour of multi-drug resistant pathogens aboard the International Space Station (ISS).

Relevance:

Facts for Prelims

About Enterobacter Bugandensis:

  • Introduction: Enterobacter bugandensis is a relatively new species within the Enterobacter genus. It was first identified in 2013, isolated from bloodstream infection cases in Uganda.

Key Characteristics:

  • It is a Gram-negative, rod-shaped bacterium.
  • Similar to other Enterobacter species, E. bugandensis is typically found in diverse environments, including soil, water, and the gastrointestinal tracts of animals and humans.
  • This bacterium can cause various infections, mainly in immunocompromised individuals. The infections include bloodstream, respiratory, urinary tract, and wound infections.
  • E. bugandensis has shown resistance to multiple antibiotics, complicating treatment efforts.
    • The resistance mechanisms may involve beta-lactamase production, efflux pumps, and mutations that reduce drug uptake.
What is the Multi-Drug-Resistant Pathogen?
  • Definition: A multi-drug-resistant (MDR) pathogen is a microorganism that has developed resistance to multiple antimicrobial agents, typically three or more categories of antimicrobials.
  • Scope: This resistance is observed in various microorganisms, including bacteria, viruses, and parasites.
    • The most concerning forms of MDR for public health are MDR bacteria that resist multiple antibiotics.

-Source: Down To Earth


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