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Ebola Virus Disease


Recently, Uganda declared an end to an Ebola virus outbreak that emerged almost four months ago and claimed the lives of 55 people. The move was confirmed in a statement issued by the WHO.


GS II: Health

Dimensions of the Article:

  1. About Ebola Virus Disease
  2. How does it spread?
  3. What are the symptoms?
  4. How can it be diagnosed?
  5. Treatment

About Ebola Virus Disease

  • The first instances of the disease, formerly known as Ebola Hemorrhagic Fever, were discovered in Guinea in December 2013.
  • Later, the illness spread to the nearby countries of Sierra Leone and Liberia.
  • Bundibugyo, Sudan, and Zaire are three of the six strains that have historically caused significant outbreaks.
How does it spread?
  • The Pteropodidae family of fruit bats is regarded to be a natural host for the Ebola virus.
  • The virus travels from human to human and is acquired by people from wild animals (through broken skin or mucous membranes).

What are the symptoms?

  • Fever
  • Fatigue
  • Muscle pain
  • Headache
  • Sore throat
This is followed by:
  • Vomiting
  • Diarrhoea
  • Rash

How can it be diagnosed?

  • Clinically separating EVD from other infectious disorders such malaria, typhoid fever, and meningitis can be challenging.
  • Numerous pregnancy symptoms and Ebola disease symptoms are remarkably similar.
  • The following diagnostic techniques are used to confirm that symptoms are brought on by Ebola virus infection:
    • Enzyme-linked immunosorbent assay for antibody capture (ELISA)
    • RT-PCR assay (reverse transcriptase polymerase chain reaction)


  • The Ervebo vaccine has been shown to be effective in protecting people from the species Zaire ebolavirus
  • Two monoclonal antibodies (Inmazeb and Ebanga) were approved for the treatment of Zaire ebolavirus (Ebolavirus) infection in adults
  • Remdesivir was also tested as an Ebola treatment.

-Source: The Hindu

December 2023