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How did India develop genome edited rice?

Development and Varieties

  • India becomes the first country to develop rice varieties using genome editing technology.
  • Developed by scientists from ICAR and allied institutions.
  • Two new rice varieties announced:
    • DRR Dhan 100 (Kamala): Derived from Samba Mahsuri.
    • Pusa DST Rice 1: Derived from Maruteru 1010 (MTU1010).


Relevance : GS 3(Agriculture ,Science)

Unique Characteristics of the Varieties

DRR Dhan 100 (Kamala):

  • Higher yield: 5.37 tonnes/ha vs. 4.5 tonnes/ha of Samba Mahsuri.
  • Drought-tolerant and climate-resilient.
  • High nitrogen use efficiency.
  • 20 days earlier maturity, saving water, fertilizers, and reducing methane emissions.

Pusa DST Rice 1:

  • Yield under stress: 3,508 kg/ha vs. 3,199 kg/ha of MTU1010.
  • Tolerant to inland and coastal salinity, and alkaline soils.
  • 9.66% to 30.4% yield advantage under various stress conditions.

Technology Used

  • Employed genome editing techniques: Site-Directed Nuclease 1 (SDN-1) and SDN-2.
  • SDN-1: Induces mutation without external guidance.
  • SDN-2: Repairs gene with guided editing but without inserting foreign DNA.
  • No use of SDN-3, which involves foreign gene insertion (true GMOs).
  • Hence, these are not considered Genetically Modified (GM) crops.

Significance for India

  • Addresses climate change-related stress: drought, salinity, pest resistance.
  • Aligns with food security goals amid growing population and limited resources.
  • Potential to reduce dependence on GM imports and improve domestic seed innovation.

Controversies and Objections

  • Farmer backlash: Venugopal Badaravada (ex-ICAR governing body member) called the claims premature and demanded transparency and accountability.
  • Expelled from ICAR after his remarks.
  • Activists’ concerns:
    • Alleged lack of field-level data and trials.
    • Legal concerns over India’s deregulation of gene-edited crops.
    • IPR issues: Fears of corporate control and erosion of seed sovereignty.
    • Genome editing not necessarily precise or risk-free, per some scientific literature.

Regulatory and Legal Status

  • Genome editing using SDN-1 and SDN-2 is exempt from GM crop regulations in some countries (including India currently).
  • ICAR claims no foreign gene is present, hence no GM label.
  • Supreme Court is still hearing a case on GM crop regulation; any precedent here could influence future approvals.

Next Steps

  • Seeds to be available after regulatory clearance within 6 months.
  • Large-scale seed production expected over 3 crop seasons.

May 2025
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