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Rotavirus

Rotavirus is a leading cause of severe diarrhoea and death among children less than five years of age.

It is responsible for around 10% of total child mortality every year.

Rotavirus-Signs and Symptoms:

  1. Kids with a rotavirus infection have fever, nausea, and vomiting, often followed by abdominal cramps and frequent, watery diarrhea.
  2. Kids may also have a cough and runny nose.
  3. Sometimes the diarrhea that accompanies a rotavirus infection is so severe that it can quickly lead to dehydration.
  4. As with all viruses, though, some rotavirus infections cause few or no symptoms, especially in adults.

Transmission:

Rotavirus is transmitted by the faecal-oral route, via contact with contaminated hands, surfaces and objects, and possibly by the respiratory route. Viral diarrhea is highly contagious.

Rotavirus upsc
  • Currently, two vaccines are available against rotavirus:

Rotarix (GlaxoSmithKline): is a monovalent vaccine recommended to be orally administered in two doses at 6-12 weeks.

Rota Teq (Merck) is a pentavalent vaccine recommended to be orally administered in three doses starting at 6-12 weeks of age.

Monovalent vaccine and Pentavalent vaccine

  • Monovalent vaccines are designed to immunize against a single antigen or single microorganism.
  • Pentavalent vaccine provides protection to a child from five life-threatening diseases – Diphtheria, Pertussis, Tetanus, Hepatitis B and Haemophilus Influenzae type b (Hib).
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